Serine

A non-essential amino acid involved in metabolism and brain function.

Last reviewedJune 16, 2026

Plasma

sample type

~5 mL

blood needed

~7 days

results in app

Morning, fasting

best timing

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Why test Reference ranges What you'll learn What affects it How testing works Sources FAQ

In short

Serine is a non-essential amino acid your body can make. It is a building block for proteins and feeds into the production of glycine, cysteine, phospholipids and the methyl groups used in many reactions. It also supports nerve and brain function.

Comprehensive Health Check

Reviewed against DGKL reference practice.

Why test this?

Plasma serine is part of a full amino acid profile and reflects protein intake and one-carbon metabolism. Unusual levels can point toward rare inherited disorders of serine synthesis, so it is read in the context of the whole profile.

What is a normal result?

Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.

Adult reference values as used by Aniva. Ranges are guidance and can vary by laboratory and method.

Group	Normal range
Adults	55 to 146 µmol/L

Sources: Mayo AAQP Test Definition

Your Aniva report reads your result against these values together with your age, sex and the rest of your panel.

Ranges are guidance and vary by lab and assay, aligned with DGKL practice. Always read your result against your own lab's reference interval.

What insights will this test give you?

Whether serine sits in the usual adult fasting range.
Context for glycine and one-carbon metabolism.
In rare cases, a clue that supports a closer look at serine synthesis.

What can affect this result?

What can skew the result

Results are affected by recent diet, recent protein intake, fasting state and the time of day the sample is taken.

Best interpreted with

Read as part of the full plasma amino acid profile.

How is this tested?

Sample

Plasma

Blood needed

~5 mL

Method

Ion-exchange chromatography or LC-MS/MS

Best timing

Morning, fasting

Sources. The evidence behind this

Mayo Clinic Laboratories: Amino Acids, Quantitative, Plasma

Common questions

Which Aniva panels include this marker?

Amino Acids

These tests assess essential, non-essential, and branched-chain amino acids, plus related metabolites and functional ratios.