Compares how varied your red blood cell sizes are against their average size, as an early quality check on red cell production.
Two values from your blood count go into this ratio. RDW, the red cell distribution width, describes how much the size of your red blood cells varies. MCV, the mean corpuscular volume, is their average size.
Dividing one by the other gives a measure of variation relative to size. It is calculated from your existing blood count, so it needs no extra sample.
Two people can have the same average red blood cell size and very different blood. One has cells that are all much the same, the other has a mix of small and large. This ratio captures that difference in a single number.
A rising ratio usually means your marrow is turning out red blood cells unevenly, which shows up early in iron, vitamin B12 or folate shortfalls, often before haemoglobin drops. A steady low ratio suggests production is consistent.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
Adult reference values as used by Aniva. Ranges are guidance and can vary by laboratory and method.
| Group | Normal range |
|---|---|
| Adults | 0.11 to 0.16 %/fL |
Sources: MedlinePlus, National Library of Medicine: RBC Indices
Your Aniva report reads your result against these values together with your age, sex and the rest of your panel.
This is a calculated value, so anything that affects RDW or MCV affects it. Recent transfusion, a mix of two different deficiencies at once, liver disease and alcohol use all shift the underlying values. It supports a picture rather than making a diagnosis on its own.
Read together with RDW, MCV, haemoglobin, ferritin and vitamin B12, and next to the Mentzer index where thalassaemia trait is a question.
What does a high RDW/MCV ratio mean? It suggests your red blood cells vary more in size than usual relative to their average, which often points to iron, vitamin B12 or folate running short.
Do I need an extra blood draw for this? No. It is calculated from values already in your blood count.
Do I need to fast? No. Eat and drink normally.
What can affect my result? Recent transfusion, two deficiencies at once, liver disease and alcohol use all move the underlying RDW and MCV.
How long do results take? Results are usually ready in about 10 days.
What should I discuss with my clinician? Ask how this sits next to your ferritin, vitamin B12 and folate, and whether the pattern warrants iron studies.
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